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Typhoid Vaccine

Trade name: Typhim Vi

Use and Mode of Action:
Typhoid vaccines are used against typhoid fever in individuals at high risk of exposure to the infection. These individuals are travellers to countries where hygiene is poor or drinking water unsafe, and where the traveller is likely to be placed at risk. Salmonella typhi is the species of salmonella most commonly associated with typhoid fever, which is an invasive infection characterised by fever, toxaemia, abdominal pain, constipation or diarrhoea. Untreated, it has a mortality rate of 10-20%

Dosage and Frequency (based on adult dosage):
0.5ml by deep subcutaneous or intramuscular injection

Side Effects:
Infrequent. Local reactions, such as pain or swelling at the injection site may occur 48-72 hours after administration

Contraindictions:
Hypersensitivity (severe allergic reaction)

Drug Interactions:
None specific

Onset of Action:
Vaccines should be given approximately 2 months prior to exposure to possible infection (if possible). However vaccines should always be administered even if the time from vaccination to exposure is less than this period.

Duration of Treatment:
see dosage and frequency.

Alternative Medicines:
None known to be as effective as standard vaccine.

Overdose Danger: Theoretically not possible as injection is by a pre-filled syringe.


Sat, Jul 31, 2010




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